Wednesday, November 21, 2012

Beta day

At 9dp5dt (14 dpo): 161!

For those not on the crazy train, my miscarriage betas were 74 and 89. The chemical pregnancy was an 8, and Small Boy was 115.

My next beta won't be until Monday (wtf??? RE Y U HATE ME) All y'all keep your fingers crossed for an appropriately rising level. But... so far, so good.

Until then, happy turkey day to them as eats turkey!

Saturday, November 17, 2012

5dp5dt

Taken 5 minutes after dippin'. Got a bit darker after it dried. Faint, but by no means the most negative test I've ever seen.

I'm quietly, hesitantly pleased. I mean, I've had pee sticks that looked like this turn into miscarriages, twice. But I've also had pee sticks that looked like this turn into an absolutely hilarious 3 year old.

I am unreservedly pleased with one aspect of my foresight. When I asked the Magic 8-ball, I didn't just ask "will I get pregnant" -- I asked "will I see a positive pregnancy test this cycle?" Now that it's been unequivocally proven wrong, I can disregard the entire prophecy. Otherwise I know that right now I'd be convinced that the "no" was foretelling an impending miscarriage. Other TTC crazy superstitious atheist agnostic pagan Jews, take note!

So now it's just hanging on until my beta on Wednesday, and (hopefully) the repeat on Friday. Here we go!





Thursday, November 15, 2012

Yesterday and today

Yesterday I felt serenely, even smugly confident that I was pregnant. I could just feel it, you know? I even peed on one of my cheapie internet pregnancy tests. Yes, for anyone keeping score, that was two days past transfer, and no, no excuse about "peeing out" the trigger; on a frozen cycle there is no trigger. That was all crazy me. So was the test I took this morning (all snowy white, of course).

Today I feel very sure that I'm not. My excellent piece of evidence is this: I have a promotional Magic 8 ball that I got as a trade show giveaway. It has been very accurate in the past. It said I'm not pregnant. Q.E.D.

Of my positive pregnancy tests, I got one at 5dp5dt (miscarriage), one at 4dp5dt (Small Boy), one at 8dp5dt (chemical), and one at 4dp5dt  (miscarriage).

This part is... hard.

Tuesday, November 13, 2012

Well, that's done.

Accomplished in the past week:

1) Re-elect President Obama;
2) Pass marriage equality legislation in my state;
3) Transfer embryos to uterus.


As you can see, I've been busy.

All kidding aside, it's been an odd few weeks. I've been tied up in knots upon knots about the election. It's not something I like to think about, but for the past 15 (fifteen. FIFTEEN) years we've been coping with the fact that Her Indoors is not an American citizen. We've patched temporary visas together legally so far, but with very little sense of security. If Obama manages to do something about DOMA during his second term, things could change for us in an earth-shattering way. I knew there was a zero percent chance of anything like that happening under a President Romney, so... I was pinning a lot of hope on this election. Not to mention the whole marriage equality thing which was/is incredibly important to me. So between one thing and another, the past few weeks have been a blur of anxiety and hopefulness.

On that subject: I have had major lining-related setbacks in the past, so I was pretty nervous about my lining check on Nov 5. I was delighted when they found my lining to be 8.79mm -- this is not rockstarish (back before Asherman's, I used to produce 11-14mm) but it's comfortably above the 8mm cutoff that my clinic uses. Previous cycles had settled down around 6.5mm. I know there are a couple of others out there struggling with lining issues, so here's a summary of what might have made a difference for me. There are details regarding vaginas below, but I figure anyone grossed out by that probably isn't reading my blog.

What I did

  • Delestrogen shots instead of estrogen pills. I think this made a big difference for me. With my last two FETs we piled on the pills in hope of fattening my lining. This gave me a pounding headache, constant nausea, and a skimpy lining, though my E2 was >1000. Delestrogen, on the other hand, has given me physiologically reasonable level of 294, no side effects, and a decent lining. Totes worth the butt-shot every third night.
  • Viagra. The doctor at Big Shiny Fertility Factory doesn't believe in Viagra to improve lining. I do. Rather than attempting to argue the point, I just quietly procured a passel of off-brand 25mg pills from an obliging Indian pharmacy and tucked one Up There four times a day from the start of estrogen to the first day of progesterone. Since the relevant study was done using suppositories, I first tried an elaborate scheme to construct suppositories with a pill-crusher, microwave, and cocoa butter inserts. This was tremendously messy and tremendously tedious. The next thing I tried was simply stuffing one into the relevant tract. Worked beautifully, with minimal muss or fuss. A tip to anyone trying this at home: it worked even better when I inserted it with 1ml of Preseed, the kind that comes in the tube with the applicator. Most effective method was to draw up 1ml of the Preseed, turn the applicator with the open end facing the ceiling, draw the plunger back a bit more, and balance the pill on top of the lube.

    Incidentally, I chose the Preseed not because I was afraid of some other lube damaging embryos or whatever, but because Preseed is pH-neutral, has no glycerin, and (most importantly) had just the right applicator to fit a Viagra pill into. $20 at Target.
  • Vitamin E. For this I didn't actually follow the study protocol of 600 mg/day; I used Dr. Marsh's protocol of 1000 mg/day. Dr. Marsh is an Asherman's expert who's seen a lot of scrawny linings. I really believe this made a difference for me, maybe as much as the Viagra -- when I had my post-surgery hysteroscopy during an unmedicated cycle I had a pretty great lining (9 mm) and I wasn't taking anything but the Vitamin E then. But I typically do worse on exogenous estrogen, so I am glad I did both the Viagra and Vit E.


What I didn't do


  • Acupuncture. I totally believe it can be helpful, but I was so busy that I just didn't get to this time round.
  • L-arginine. I started out taking 6g a day (12 pills!). After 4 days I had rotten heartburn and decided to just give it up. Plus, its mechanism is basically the same as Viagra's (although it's taken orally), and I was afraid of Overdoing It.

Transfer was smooth. The receptionist said "Good luck, ladies!" as we walked in, which pleased me. We may be lesbians, but we're still ladies, dammit. Gauged the water/bladder fullness pretty well; I was uncomfortable, but not in agony. Was not offered a picture of the embryos, which was a bit disappointing, but which I have to admit is sensible. Blastocysts were fair quality upon thaw; I've not too fazed, though, considering the fact that my only take-home baby has come from the worst-quality embryo I ever transferred. Pretty is as pretty does, you know?

So now... we wait. And I eat pineapple, out of a sense of tradition and ritual. And bathe in the knowledge that, positive or negative, BFN or BFP, come Jan 1 we can get freaking married, and come Jan 20 we'll be watching President Obama up there on the podium. I've gotten two out of my three wishes for November. I'm hoping for a hat-trick, but no matter what happens, it's been a stonking good month.

Wednesday, October 24, 2012

Begin again

I keep starting posts and fading out.

The Asherman's surgery in May was, by all accounts, a success. Dr. Isaacson was lovely, in accordance with all the recommendations I got from the Asherman's mailing list. He found one major band near the cornu (where the tube attaches) and some minor adhesions near the cervix. He feels pretty sure that the largest adhesion was from the c-section; apparently, when they're done popping out the baby, they sponge down the uterus. And either I was sponged too hard or -- more likely -- my body simply didn't like being sponged, and reacted by forming an adhesion.

Learning that it was probably the c-section, not the D&C, is kind of mixed. On one hand, it's comforting to know that it probably couldn't have been avoided. If someone asked me if I would pay the price of Asherman's to safely have Small Boy, I'd agree instantly. At least I got something out of the deal, you know?

On the other hand, it means that Dr. Stewart missed the adhesions during the quite-hasty SHSG. And that last year's pregnancy never had a chance, and that those embryos might have well been flushed down the toilet, and that all that horror could have been avoided.

Second-guessing does no good in the real world, so of course I try to spend no more than 80% of my waking hours running mental simulations of alternate universes.



But all that's old news. See? I put a line under it.  It's old news because yesterday I had my first Delestrogen shot for my FET cycle. HOLY CRAP that hurt. I'm a spoiled little princess who's only ever done progesterone in ethyl oleate with slender 25ga needles. The 22ga was like sticking a fucking drinking straw into my glute.

Her Indoors was, as ever, both charming and useful. After giving me the shot, she eyed my prone, gasping form sympathetically.

Her: Does it hurt?
Me: YES
Her: If I slap you, it might help.
Me: SURE WHATEVER
Her: delivers ringing slap to my buttock, right where the shot went
Me: ... wow, that totally helped.

This brief domestic scene illustrates two points about our life nicely:

1) Her Indoors is smart about all sorts of things. There's an explanation having to do with the dissipation of oil in the muscle and circulation and nerve endings and stuff.

2) I trust her really a lot.



So yeah, new cycle!

If my lining does as it ought -- and that's a big "if" -- my scheduled transfer date is November 12. In 2008, on the cycle that resulted in Small Boy, my transfer was November 15. In 2011, on the cycle that resulted in the zombie pregnancy, my transfer was November 10. I guess this is just the time of year that I like to put embryos in my uterus.

Here we go!
Here we go.
Here we go...

Wednesday, May 2, 2012

Day 6 embryo report

Nine. Nine. Beautiful, beautiful nine fucking frozen embryos.

Two made the grade yesterday at 7 am or so; one more joined them at 10:30 am, so that's three frozen on day 5. An additional six joined on Day 6.

Day 6 have been sometimes found to be less likely to implant than are day 5; a 2001 study found a 50% reduction (from 60% to 30%) -- but a much larger 2006 study found almost no difference (32% vs 28%).  The fact that the 2001 5-day blast group had a pregnancy rate of 60% makes me think that their population must have been a bit unusual, anyway -- I don't know of anywhere that can claim a 60% pregnancy rate, unless all their participants were 20!

Anyway, even the worst represents a good solid pregnancy rate, and did I mention six of them fomg.

And -- I might need them. I freaked myself out yesterday by reading a lot about Asherman's Syndrome, and it sucks. Makes it harder to get pregnant, and makes miscarriage a lot more likely; one source reports a miscarriage rate of 45%. Just what I need, huh? But it's also easy to find stories of women with Asherman's who have three or four miscarriages and then a live birth. If I have the balls to keep rolling the dice, there's a decent chance I'll eventually win.

Basically, if I go ahead here, I have to be prepared that it may take a few false starts. I have to figure out how to not go completely mental the way I did with the other two miscarriages. I have to figure out how to stay sane. I probably have to stay out of the forums where people assume that a positive pregnancy test means a baby.

This all sounds grim, and I was pretty damn down last night when I thought I had two embryos, or just one try. But now that I have 9, which could well be four tries, I'm feeling much more hopeful.

I think I am tough enough for this. I think I can do this. It helps to know that I can stop any time. Her Indoors is more than okay with keeping our family the way it is -- frankly, she's indulging me on this endeavor. There will be zero pressure on me to keep going. If it's too much, I can pause or walk away. It's not like my family sucks the way it is, you know? Yes, the wordless longing of my heart is for one more. Yes, I feel like there's still someone missing. But really, I could be wrong. I've been wrong before. Maybe our family's the way it's supposed to be. I have to try, though.

For the historical record, our family roster now consists of:

Hatching blasts:
2 - AA Good
2 - BB Fair

Expanding blasts:
2 - AA Good
2 - AB Fair
1 - BB Fair


FWIW, I'm not particularly hung up on embryo quality. Have I mentioned that a little 2BB blastocyst (different rating system, but prob equivalent to the BB Fair) turned into our entirely acceptable son? And I have seen many perfect embryos come to naught. Anecdotal, yeah, but it's anecdotes that make up my story, so.

In conclusion, beautiful, beautiful nine!

Tuesday, May 1, 2012

Day 5 embryo report

2 expanded blast (will be frozen)
7 early blasts, 6 fair, one poor
2 morulas
1 9+ cells
3 no change, on probation
2 no change, discarded

The early blasts and possibly the morulas are still in the game for Day 6. But at least we've got two safely in the freezer.

It's not what I'd fantasized about (I imagined my nurse's voice saying "all 9 were beautiful and we froze them!"), but it's far better than I'd feared (i.e., nothing to freeze, a big waste of a cycle).


*chews nails*