Friday, November 28, 2008

How my family took it...

Well? They're excited? They were stunned? They're calling me every day? My mom read up on OHSS and quizzed me to make sure that I didn't have a severe case (I don't)?

I have such mixed feelings about having told them. Part of me wants to bask in the attention and approval, which I am finally receiving in buckets. The last thing I did that they really approved of was 12 years ago, when I enrolled in grad school. I dropped out a few years later, became a lesbian, it's all been downhill since then. They love me, and they try, but I can tell that they have to work really hard to be supportive of me and my choices.

I get tolerance, and I'm grateful for that. I don't get offended when they discuss, in front of me, what gift can possibly be large enough for them to give my sister and her husband for their upcoming 15th wedding anniversary (my darling and I have been together for 11 years, and no, I'm not holding my breathe waiting for a card). I reinforce them heavily every time they mention my partner's name or send her greetings or remember her birthday (which they have done two years running now -- major progress).

But yeah, I get tolerance. I don't get approval. Having it now is freaking me out a little, and maybe making me a little angry.

I didn't feel that I had much of a choice about telling them, since there was no way I could travel as huge and OHSS-y as I am. But I can't get past the thought: if I miscarry again, then not only will I be heartbroken but I'll have disappointed my parents.

In other news, keep staring at my taut abdomen. Whatcha doin in there, huh? Whatcha doin? Still alive? Gimme a sign, here.

Wednesday, November 26, 2008

11dp5dt/16dpo beta

224.

Progesterone: 298.


Doubling time: 49.9 hours. Not rock-star, but well within normal range (as opposed to my last 14-16dpo set, which were barely within normal range).

In other news, I'm enormous, bloated and largely immobile thanks to OHSS. Accordingly, I had to cancel plans to fly up to Boston to see my folks for Thanksgiving, which I knew would disappoint them terribly. Accordingly, I told them why.

holyshitholyshititoldthem

it felt wonderful but so, so naughty.

just. I don't know. I'm sitting here very quietly, sipping my V8 and homemade electrolyte drink, trying to make peace with the hope that keeps flaring within my heart. It seems so very dangerous, but it simply will not go away.

Monday, November 24, 2008

9dp5dt/14dpo beta

115.

Progesterone: 320.

Over the weekend I
  1. peed on 1,214 sticks
  2. convinced myself that the line was getting lighter, not darker
  3. had weeping fits since it was clearly all over
  4. gathered up all my peesticks and begged Her Indoors to hide them very, very well.
I think some of the leftover crazy from the miscarriage is bubbling over. I just can't help thinking of how high I was then and how fast and hard I fell. But that's the way of it, isn't it? There's no way to want something this precarious this much and not be in terrible danger.

I have been staring at the clock all day. These are the things I mentally rehearsed hearing:
Your results are back -- the beta was 8 and you can stop your medication.
The beta was 18

The beta was 26
The beta was 54

We're supposed to call for results between 3 and 4. At 2:59 I picked up the phone and the moments I was on hold I could have measured by the heartbeat pounding in my ears.

115 is a solidly normal beta. Not high, not low. Last time at 14dpo my beta was 74, on the low side, although not wildly so. 115 is a happy number. 115 is a healthy number. 115 is just fine.

In other news, no surprise, I have developed a mild case of OHSS. At least, I thought it was mild; when I went in to have my blood taken this morning, Inappropriate Lab Admin Asst took one look at me and said "You blowin' up again?" Me: "Looks like." Anyway, besides the OHSS, I feel pretty good. Not a lot in the way of symptoms except cramps, which don't concern me -- I figure it's just the embryo bedding down. No spotting at all.

Thanks so much for all of the good wishes and crossed fingers on my previous post. Really can't say how much it means to me that you are all out there rooting for us. I could never have anticipated the extent to which this has become a group project.

Next adventure: Wednesday's repeat beta. Since you all did such a splendid job with the finger-crossing for this beta, your next assignment is think doubley thoughts.

Thursday, November 20, 2008

5dp5dt

I'm grateful. I'm hopeful. I'm cautious, but... so far so good, right? Yeah. Ever since the brief time I was pregnant I've been missing this, longing to feel this again -- the humming, the sense of busyness within my body, strange and wonderful, explosive with possibility.

Right here right now I am so glad to be here again. Keep your fingers crossed for me, y'all.

Monday, November 17, 2008

2dp5dt: the roller coaster continues



After the plunge from Saturday's embryo-quality news, I have been lifted up into the atmosphere again by the following news:

Eight of the remaining embryos turned into "very nice quality" (4AA or 4AB) by day 6 and were frozen! Eight! Eight! I expected to have nothing make it to freeze. And of course this is making me much more hopeful for the ones I have inside me. Maybe this batch of embryos are just slow but good-quality growers. That's okay with me.

Saturday, November 15, 2008

Transfer day: another dose of mixed news

Good: the spotting, which was only slight, stopped entirely!

Not so good: I had 16 good-looking embryos on day 3. As of today, day 5, I had a couple of mediocre-looking embryos. First round we transferred one 4AA. This time the best we could do was 2BB. No one knows why, of course.

We had such good results the first time that I was barely worried about the embryos between days 3 and 5. Since worrying is how I stave off disaster, obviously this happened because I failed to worry properly. This mistake will not be repeated.

It was pretty upsetting to sashay in there, full of confidence, and get the news. But just because the chances are somewhat reduced doesn't mean that they're zero; babies are born all the time from less-than-perfect embryos.

Well, it is what it is. It's all over now but the waitin' and the hopin'.

Friday, November 14, 2008

4 days past ER: mostly sunny with a few clouds

Mostly sunny:
As of yesterday, the embryos were doing great -- 16 of the 19 were "doing well"; 8 of those were 8 cells grade 1. We're set for a transfer tomorrow. This is really really great.

Wednesday was my birthday, and it was nice.

A few clouds:
I've had slight cramping and spotting. I thought to myself "hey, nothing to worry about, it's so slight" but called the RE just to be safe. Apparently telling your RE that you're spotting the day before transfer wins: stat bloodwork, a pelvic exam, an ultrasound, an Estrace prescription at the ready, and the note that if you start bleeding harder to call right away and we'll cancel the transfer.

Erp.

I'm trying to stay cool. It could all be just fine.

Other slight clouds: the ultrasound showed some fluid sloshing around my abdominal cavity; although I feel okay, I haven't dodged the OHSS thing entirely. I'm to chug electrolyte drinks. Also, my good right arm vein is mostly used up -- guess it gets scarred after a while. The vein I have on my left arm is not very accessible, so if my right arm poops out they will have to start on my hands, which sounds unsightly and unpleasant.

And that's the news.

Tuesday, November 11, 2008

1 day past ER: all good news!

Okay, this is just crazy.

It's Tuesday. As of last Friday I had five mature-looking follicles and we were still consdering cancelling the cycle and doing an IUI. As of Saturday, when I triggered, that number had doubled.

And as of Mondays' retrieval...

23 eggs. 21 mature. 19 fertilized.

19. 19. Where the hell did those come from? No one saw that coming. My doctor sure didn't, having carefully prepared me -- he was estimating 8-10, then revised his numbers upward to 10-15. I said I'd be ecstatic with 15 and happy with 10.

Of course there's no guarantee of anything, but the bigger the starting number the higher the chance of having multiple strong, healthy embryos.

The witches' brew of metformin - high stims - even higher stims - no metformin seems to have produced a bumper crop without making me sick as a dog in the process. As of today I'm sore and moving slowly, but I'm nowhere near the hit-by-a-truck shape I was in first cycle. I am lumbering to the bathroom all on my own, and it doesn't hurt to cough or, you know, breathe. I took three days off from work (vacation days, so I wouldn't have to have The Conversation) and I think that by Thursday I'll be in fightin' form.

Worrying will recommence tomorrow. Today I am just delighted.

Saturday, November 8, 2008

Day 11: Trigger Day

Almost all good news today! My ovaries are humming. A solid handful of follicles popped up overnight. We're now hoping for 10-12 total, much better than I'd feared.

Other good things: my birthday is on Wednesday, and today I went on a shopping spree and snagged the Wii Fit I'd been wanting, as well as a pile of Nintendo DS games. These should keep me out of trouble during any OHSS-related confinement. Which brings me to the only not-perfect thing, which is that my doctor wrote Get your electrolyte and protein drinks ready! on the bottom of my instruction sheet. Underlined. I take it to mean that he expects me to get OHSS again.

Well, we're reasonably prepared, and even if I do get it I expect the whole thing will be less traumatic second time around -- I'll be uncomfortable, but at least I won't be scared.


Oh! And when we were wandering around the mall, I saw this sculpture in the Pottery Barn window and was immediately drawn to it. I wasn't sure why -- according to the label it's a reindeer, and I don't celebrate Christmas and in fact have a slight Jewish-girl jealousy/aversion to Christmasphenalia. And the percentage of times when I walk by a store window, see something, and then go in and buy the thing in the window at full retail approaches zero.

But, as I was looking through the window, my darling reasonably suggested that this sculpture is in fact quite evocative of the Celtic stag-god Herne/Cernunnos. He's a powerful male fertility aspect. I bought the large one, with the leaves blooming from his antlers, and he's making me very happy. My eyes like looking at him, even though he's taking up half of the bedroom vanity.

I intend to hang necklaces on him eventually, but have been warned not to do so until I'm already pregnant, so as not to feminize the powerful male fertility aspect by making him look like a pretty pretty princess.


Update: I have triggered! I am now a ticking time bomb of superovulation! Whee!

Friday, November 7, 2008

Day 10: the good and the bad

The bad:
At this point in the last cycle, I had 6 correctly-sized follicles. This cycle, even with more medication, I have 5. There is no way to know why my ovaries are so sluggish this cycle. For heaven's sake, on a lower dosage I got 21 mature eggs my first cycle. It could be the metformin, but I've never heard anyone else say that metformin ruined their response.

The good:
My estrogen is much, much higher than it was last cycle. This bespeaks of the possibility of lurking eggs. A couple more may well fatten up and surprise us. We're giving my ovaries another day to cook and cutting down the dosage.

Herein I enclose a table for my own record-keeping, enjoyment & convenience, because I find hand-coding HTML tables strangely soothing:


E2
Cycle 2Cycle 3
Day 4134154
Day 6445491
Day 89101401
Day 10 1938 (trigger)
3226
Day 11 (trigger)
4065 (trigger)

Of course, this also means that the risk for OHSS is going back up, but
  1. It's less likely with so many fewer follicles, regardless of the E2;
  2. I do not care.
Another scan tomorrow, likely trigger tomorrow night, for a Monday retrieval.

So that's the news. On the whole I'm feeling much much happier than I was a few days ago, when it seemed that even pumping up the dose wasn't doing anything to make this cycle different from last. At least things are moving. Or at least I'm high on estrogen.

Sunday, November 2, 2008

Day 5 of Stims: not so good

My E2 was pretty low on Saturday, as low as it was last time with my "poor response" cycle, despite the higher dose of stims. It must be the metformin.

We raised the dose and I quit taking the metformin. If I have <10 follicles on tomorrow's scan we'll cancel this cycle and consider converting to an IUI. If you know anything about the issues here, you know that this would be a hideously hilarious choice for me.

Most people would only cancel a cycle with <5 follicles, but this is my last chance, my last insurance-covered cycle. I want it to be everything it can be. I don't even care about OHSS any more. I just want a big old crop of eggs.

I will admit that my first thought about canceling the cycle and trying again was oh crap, not more birth control pills.